ZEB2
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| ZEB2 | SIP1,ZFHX1B, HSPC082, SMADIP1,KIAA0569, SIP-1, SIP1 | zinc finger E-box binding homeobox 2 | NM_014795 |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome. Alternatively spliced transcript variants have been found for this gene.
This gene is higher expressed in human cells cells 23 h after Ebola infection but generally lowly expressed. In bat cells the gene is higher expressed in general.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 4 | 4 | 3 | 4 | 2 | 45 | 2 | 3 | 11 |
Read_Max |  | R. aegyptiacus | Transcriptome | 144 | 118 | 85 | 94 | 75 | 144 | 104 | 109 | 143 |
Read_Max |  | R. aegyptiacus | Genome | 157 | 92 | 72 | 119 | 68 | 87 | 88 | 132 | 152 |
DESeq | | H. sapiens | Genome | 11.15 | 22.42 | 14.9 | 29.52 | 9.13 | 552.37 | 22.05 | 12.19 | 83.64 |
DESeq | | R. aegyptiacus | Transcriptome | 1903.08 | 1537.72 | 1117.48 | 1503.61 | 1318.39 | 2491.66 | 1639.57 | 1216.35 | 1290.32 |
DESeq | | R. aegyptiacus | Genome | 2447.54 | 1882.87 | 1519.69 | 2062.85 | 1824.88 | 3472.39 | 2241.19 | 1669.94 | 1751.77 |