CNN1

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
CNN1 SMCC, Sm-Calp, HEL-S-14 calponin 1, basic, smooth muscle NM_001299 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity (by similarity).

No or very low expression in human cells in general, however, some more expression visible in Ebola-infected cells after 23 h of infection. Low expression in bat cells.

Show legend

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome5 5 5 4 2 31 9 8 3
Read_Max
batR. aegyptiacusTranscriptome 21 22 8 17 24 20 18 26 16
Read_Max
bat_genomeR. aegyptiacusGenome 24 20 7 22 10 7 15 28 15
DESeq
humanH. sapiensGenome 23.33 14.26 8.94 20.39 5.88 297.08 22.05 13.79 12.96
DESeq
batR. aegyptiacusTranscriptome 81.65 113.55 33.98 76.08 92.99 42.06 91.1 77.01 57.86
DESeq
bat_genomeR. aegyptiacusGenome 97.97 89.44 34.59 136.27 71.43 37.86 91.09 82.47 48.8

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 23.33 20.39 22.05 -0.19 -0.08 0.11
7h 14.26 5.88 13.79 -1.28 -0.05 1.23
23h 8.94 297.08 12.96 5.05 0.54 -4.52

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 23.33 14.26 8.94 -0.71 -1.38 -0.67
Ebov 20.39 5.88 297.08 -1.79 3.86 5.66
Marv 22.05 13.79 12.96 -0.68 -0.77 -0.09

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 81.65 76.08 91.1 -0.1 0.16 0.26
7h 113.55 92.99 77.01 -0.29 -0.56 -0.27
23h 33.98 42.06 57.86 0.31 0.77 0.46

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 81.65 113.55 33.98 0.48 -1.26 -1.74
Ebov 76.08 92.99 42.06 0.29 -0.86 -1.14
Marv 91.1 77.01 57.86 -0.24 -0.65 -0.41