ATF3
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| ATF3 | Activating Transcription Factor 3 | activating transcription factor 3 | NM_001674 |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
This gene encodes a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. This gene is induced by a variety of signals, including many of those encountered by cancer cells, and is involved in the complex process of cellular stress response. Multiple transcript variants encoding different isoforms have been found for this gene. It is possible that alternative splicing of this gene may be physiologically important in the regulation of target genes.
The gene ATF3 is significantly higher expressed in bat cells 23 h after Ebola virus infection compared to rest. In human cells the 23 h Ebola dataset is the only one showing expression of the 3'UTR, which may have regulatory function.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 29 | 19 | 52 | 19 | 46 | 1401 | 35 | 45 | 67 |
Read_Max |  | R. aegyptiacus | Transcriptome | 9 | 13 | 46 | 25 | 31 | 127 | 12 | 28 | 51 |
Read_Max |  | R. aegyptiacus | Genome | 16 | 26 | 36 | 14 | 22 | 74 | 8 | 33 | 58 |
DESeq | | H. sapiens | Genome | 162.35 | 146.84 | 222.4 | 177.81 | 212.37 | 10458.63 | 257.14 | 238.41 | 528.36 |
DESeq | | R. aegyptiacus | Transcriptome | 29.56 | 35.49 | 212.33 | 100.81 | 101.75 | 516.84 | 46.61 | 102.62 | 191.69 |
DESeq | | R. aegyptiacus | Genome | 94.53 | 209.0 | 397.22 | 124.42 | 254.48 | 1117.43 | 105.71 | 233.13 | 494.02 |