GZMM
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| GZMM | GZMM, LMET1, MET1,MET1 | granzyme M (lymphocyte met-ase 1) | NM_005317 |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
Human natural killer (NK) cells and activated lymphocytes express and store a distinct subset of neutral serine proteases together with proteoglycans and other immune effector molecules in large cytoplasmic granules. These serine proteases are collectively termed granzymes and include 4 distinct gene products: granzyme A, granzyme B, granzyme H, and the protein encoded by this gene, granzyme M.
Very low noisy expression in all samples but Ebola infection after 23 h. There a higher but also noise unreliably transcript can be seen.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 2 | 2 | 1 | 3 | 2 | 11 | 1 | 2 | 2 |
Read_Max |  | R. aegyptiacus | Transcriptome | NA | NA | NA | NA | NA | NA | NA | NA | NA |
Read_Max |  | R. aegyptiacus | Genome | 0 | 2 | 0 | 0 | 0 | 2 | 2 | 3 | 0 |
DESeq | | H. sapiens | Genome | 6.07 | 3.04 | 2.99 | 7.84 | 2.63 | 83.9 | 3.63 | 2.6 | 3.17 |
DESeq | | R. aegyptiacus | Transcriptome | NA | NA | NA | NA | NA | NA | NA | NA | NA |
DESeq | | R. aegyptiacus | Genome | 0.0 | 2.74 | 0.0 | 0.0 | 0.0 | 9.14 | 4.5 | 1.59 | 0.0 |