NLGN3

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
NLGN3	HNL3, KIAA1480, ASPGX1, AUTSX1	neuroligin 3	NM_018977	pdf		NONE

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. Mutations in this gene may be associated with autism and Asperger syndrome. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

No expression in general for human cells and bat cells. In human cells cells infected by Ebola, there are a few reads visible after 23 h.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source	Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max	H. sapiens	Genome	1	2	2	2	2	15	2	2	2
Read_Max	R. aegyptiacus	Transcriptome	2	2	NA	NA	NA	NA	NA	1	NA
Read_Max	R. aegyptiacus	Genome	2	3	4	3	1	2	2	5	2
DESeq	H. sapiens	Genome	1.0	5.08	4.97	3.28	5.88	116.8	9.77	8.19	9.7
DESeq	R. aegyptiacus	Transcriptome	2.68	2.82	1.0	1.0	1.0	1.0	1.0	1.83	1.0
DESeq	R. aegyptiacus	Genome	9.45	4.56	11.16	7.9	2.23	3.92	13.49	7.93	8.56

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	1.0	3.28	9.77	1.71	3.29	1.57
7h	5.08	5.88	8.19	0.21	0.69	0.48
23h	4.97	116.8	9.7	4.55	0.96	-3.59

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	1.0	5.08	4.97	2.34	2.31	-0.03
Ebov	3.28	5.88	116.8	0.84	5.15	4.31
Marv	9.77	8.19	9.7	-0.25	-0.01	0.24

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	2.68	1.0	1.0	-1.42	-1.42	0.0
7h	2.82	1.0	1.83	-1.5	-0.62	0.87
23h	1.0	1.0	1.0	0.0	0.0	0.0

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	2.68	2.82	1.0	0.07	-1.42	-1.5
Ebov	1.0	1.0	1.0	0.0	0.0	0.0
Marv	1.0	1.83	1.0	0.87	0.0	-0.87

Differential transcriptional responses to Ebola and Marburg virus infection in cells from bats and humans

Supplemental Material