ANXA1
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| ANXA1 | ANX1, LPC1 | annexin A1 | NM_000700 |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. This protein regulates phospholipase A2 activity. It seems to bind from two to four calcium ions with high affinity. GO - Biological process: alpha-beta T cell differentiation, cell surface receptor signaling pathway, cellular response to glucocorticoid stimulus, inflammatory response, among others.
Seems to be upregulated at 23 h of Marbug virus infection in human cells. Seems to be downregulated in the control for bat cells, but upregulated in Ebola infection in bat cells. In bat cells there is a very high expression level of this gene. In the Marburg infected bat cells the gene pattern seems to change over time in comparison with Ebola and control.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 15 | 14 | 5 | 14 | 16 | 21 | 16 | 20 | 42 |
Read_Max |  | R. aegyptiacus | Transcriptome | 6926 | 6118 | 6769 | 5761 | 5448 | 6772 | 5524 | 6610 | 8083 |
Read_Max |  | R. aegyptiacus | Genome | 7861 | 6015 | 5700 | 6085 | 4647 | 4006 | 4704 | 7888 | 9045 |
DESeq | | H. sapiens | Genome | 58.84 | 37.72 | 6.96 | 78.57 | 71.73 | 112.85 | 74.69 | 72.94 | 266.31 |
DESeq | | R. aegyptiacus | Transcriptome | 22764.61 | 22599.75 | 28890.34 | 24950.21 | 26203.22 | 27881.97 | 26695.41 | 25434.18 | 26296.49 |
DESeq | | R. aegyptiacus | Genome | 23808.54 | 25003.0 | 26465.13 | 24815.46 | 26926.73 | 28895.25 | 27710.72 | 25051.54 | 26083.02 |