CXCL5

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
CXCL5 CXCL5, ENA-78, SCYB5,ENA-78 chemokine (C-X-C motif) ligand 5 NM_002994 pdf NONE

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

This gene encodes a protein that is a member of the CXC subfamily of chemokines. Chemokines, which recruit and activate leukocytes, are classified by function (inflammatory or homeostatic) or by structure. This protein is proposed to bind the G-protein coupled receptor chemokine (C-X-C motif) receptor 2 to recruit neutrophils, to promote angiogenesis and to remodel connective tissues. This protein is thought to play a role in cancer cell proliferation, migration, and invasion.

CXCL5 shows very strong induction in the late phase of Ebola and Marburg virus infection in human cells cells.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome40 26 10 42 41 406 45 48 122
Read_Max
batR. aegyptiacusTranscriptome NA NA NA NA NA NA NA NA NA
Read_Max
bat_genomeR. aegyptiacusGenome NA NA NA NA NA NA NA NA NA
DESeq
humanH. sapiensGenome 265.86 183.56 84.4 290.73 240.82 3159.21 318.55 184.05 1180.77
DESeq
batR. aegyptiacusTranscriptome NA NA NA NA NA NA NA NA NA
DESeq
bat_genomeR. aegyptiacusGenome NA NA NA NA NA NA NA NA NA

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 265.86 290.73 318.55 0.13 0.26 0.13
7h 183.56 240.82 184.05 0.39 0.0 -0.39
23h 84.4 3159.21 1180.77 5.23 3.81 -1.42

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 265.86 183.56 84.4 -0.53 -1.66 -1.12
Ebov 290.73 240.82 3159.21 -0.27 3.44 3.71
Marv 318.55 184.05 1180.77 -0.79 1.89 2.68

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h NA NA NA NA NA NA
7h NA NA NA NA NA NA
23h NA NA NA NA NA NA

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock NA NA NA NA NA NA
Ebov NA NA NA NA NA NA
Marv NA NA NA NA NA NA