VGF
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| VGF | SCG7, SgVII | VGF nerve growth factor inducible | NM_003378 |  |
NONE |  |
 |
Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
This gene is specifically expressed in a subpopulation of neuroendocrine cells, and is upregulated by nerve growth factor. The structural organization of this gene is similar to that of the rat gene, and both the translated and the untranslated regions show a high degree of sequence similarity to the rat gene. The encoded secretory protein also shares similarities with the secretogranin/chromogranin family, however, its exact function is not known.
It is weakly expressed in human cells after 23 h of Ebola virus infection and constantly but low as well in bat cells. There seems to be an expressed location upstream of the gene in human cells.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 2 | 0 | 0 | 0 | 2 | 16 | 2 | 0 | 4 |
Read_Max |  | R. aegyptiacus | Transcriptome | 6 | 8 | 16 | 5 | 5 | 11 | 7 | 7 | 12 |
Read_Max |  | R. aegyptiacus | Genome | 8 | 8 | 9 | 9 | 6 | 7 | 4 | 10 | 14 |
DESeq | | H. sapiens | Genome | 5.06 | 1.0 | 1.0 | 1.0 | 2.63 | 57.58 | 3.63 | 1.0 | 7.52 |
DESeq | | R. aegyptiacus | Transcriptome | 40.49 | 36.4 | 82.84 | 27.55 | 37.14 | 47.19 | 26.59 | 28.26 | 50.86 |
DESeq | | R. aegyptiacus | Genome | 48.13 | 41.07 | 82.57 | 49.37 | 53.57 | 50.91 | 25.86 | 42.82 | 61.65 |