CLDN9
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| CLDN9 | CLD9_HUMAN, NM_020982, NP_066192, O95484 | claudin 9 | NM_020982 |  |
NONE |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
CLDN9 encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This protein is one of the entry cofactors for hepatitis C virus. Mouse studies revealed that this gene is required for the preservation of sensory cells in the hearing organ and the gene deficiency is associated with deafness.
For this gene only in Ebola 23 h infected probe few reads mapped. In the other probes no expression took place.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 6 | 2 | 0 | 2 | 4 | 21 | 3 | 3 | 2 |
Read_Max |  | R. aegyptiacus | Transcriptome | NA | NA | NA | NA | NA | NA | NA | NA | NA |
Read_Max |  | R. aegyptiacus | Genome | 3 | 2 | 1 | 10 | 2 | 2 | 2 | 0 | 2 |
DESeq | | H. sapiens | Genome | 17.24 | 5.08 | 1.0 | 5.56 | 10.76 | 145.75 | 15.04 | 9.79 | 7.52 |
DESeq | | R. aegyptiacus | Transcriptome | NA | NA | NA | NA | NA | NA | NA | NA | NA |
DESeq | | R. aegyptiacus | Genome | 2.58 | 2.74 | 1.12 | 9.87 | 2.23 | 3.92 | 2.25 | 0.0 | 2.57 |