LY6G5C

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
LY6G5C C6orf20, G5c, NG33,G5c lymphocyte antigen 6 complex, locus G5C pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

LY6G5C belongs to a cluster of leukocyte antigen-6 (LY6) genes located in the major histocompatibility complex (MHC) class III region on chromosome 6. Members of the LY6 superfamily typically contain 70 to 80 amino acids, including 8 to 10 cysteines. Most LY6 proteins are attached to the cell surface by a glycosylphosphatidylinositol (GPI) anchor that is directly involved in signal transduction~\citemallya02transcriptional.

The gene is very low in expression in human cells and is slightly up-regulated in Ebola infected cells.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome4 4 3 3 4 19 8 6 7
Read_Max
batR. aegyptiacusTranscriptome 3 NA NA 3 NA NA 4 2 2
Read_Max
bat_genomeR. aegyptiacusGenome 0 0 0 0 0 0 0 0 0
DESeq
humanH. sapiensGenome 21.3 21.4 18.87 4.42 20.51 108.91 22.93 16.19 21.66
DESeq
batR. aegyptiacusTranscriptome 6.88 1.0 1.0 3.75 1.0 1.0 9.9 2.65 3.62
DESeq
bat_genomeR. aegyptiacusGenome 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 21.3 4.42 22.93 -2.27 0.11 2.38
7h 21.4 20.51 16.19 -0.06 -0.4 -0.34
23h 18.87 108.91 21.66 2.53 0.2 -2.33

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 21.3 21.4 18.87 0.01 -0.17 -0.18
Ebov 4.42 20.51 108.91 2.21 4.62 2.41
Marv 22.93 16.19 21.66 -0.5 -0.08 0.42

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 6.88 3.75 9.9 -0.88 0.53 1.4
7h 1.0 1.0 2.65 0.0 1.41 1.41
23h 1.0 1.0 3.62 0.0 1.86 1.86

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 6.88 1.0 1.0 -2.78 -2.78 0.0
Ebov 3.75 1.0 1.0 -1.91 -1.91 0.0
Marv 9.9 2.65 3.62 -1.9 -1.45 0.45