CYR61

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
CYR61 CCN1, GIG1, IGFBP10,GIG1, CCN1 cysteine-rich, angiogenic inducer, 61 NM_001554 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

The secreted protein encoded by this gene is growth factor-inducible andpromotes the adhesion of endothelial cells. The encoded protein interactswith several integrins and with heparan sulfate proteoglycan. This proteinalso plays a role in cell proliferation, differentiation, angiogenesis,apoptosis, and extracellular matrix formation.

Significant up-regulation in human cells cells after 23 h of Ebolainfection, otherwise low expression in human cells. There is a very highexpression in the bat cells homolog.}

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome42 52 20 63 48 476 103 78 40
Read_Max
batR. aegyptiacusTranscriptome 1838 2052 1762 1580 1335 2116 1415 1880 2172
Read_Max
bat_genomeR. aegyptiacusGenome 2120 1687 1550 2081 1141 1285 1276 2384 2469
DESeq
humanH. sapiensGenome 421.12 376.31 138.01 753.85 332.68 4271.17 972.07 619.7 422.89
DESeq
batR. aegyptiacusTranscriptome 11726.0 15689.51 16037.33 12634.48 11847.68 15530.06 12060.59 12589.11 13367.42
DESeq
bat_genomeR. aegyptiacusGenome 16084.34 16702.13 21599.23 22022.86 16154.92 22022.27 17428.0 16781.91 18402.13

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 421.12 753.85 972.07 0.84 1.21 0.37
7h 376.31 332.68 619.7 -0.18 0.72 0.9
23h 138.01 4271.17 422.89 4.95 1.62 -3.34

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 421.12 376.31 138.01 -0.16 -1.61 -1.45
Ebov 753.85 332.68 4271.17 -1.18 2.5 3.68
Marv 972.07 619.7 422.89 -0.65 -1.2 -0.55

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 11726.0 12634.48 12060.59 0.11 0.04 -0.07
7h 15689.51 11847.68 12589.11 -0.41 -0.32 0.09
23h 16037.33 15530.06 13367.42 -0.05 -0.26 -0.22

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 11726.0 15689.51 16037.33 0.42 0.45 0.03
Ebov 12634.48 11847.68 15530.06 -0.09 0.3 0.39
Marv 12060.59 12589.11 13367.42 0.06 0.15 0.09