TMEM150B

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
TMEM150B TMEM224 transmembrane protein 150B NM_001085488 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

This gene encodes a protein that belongs to the DRAM (damage-regulated autophagy modulator) family of membrane-spanning proteins. Alternate splicing results in multiple transcript variants.

Shows strange expression profiles in human cells probes and seems to be only expressed in bat cells 23 h after Marburg infection and mock.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome4 5 14 5 8 73 4 10 20
Read_Max
batR. aegyptiacusTranscriptome 2 1 9 1 0 4 3 2 8
Read_Max
bat_genomeR. aegyptiacusGenome 6 4 5 4 3 3 5 6 6
DESeq
humanH. sapiensGenome 27.38 45.87 129.07 39.78 79.04 1164.28 40.47 84.93 250.0
DESeq
batR. aegyptiacusTranscriptome 2.68 1.91 13.22 2.83 1.0 4.85 5.45 2.65 8.0
DESeq
bat_genomeR. aegyptiacusGenome 33.52 27.38 29.01 27.65 10.05 22.19 35.99 27.75 21.4

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 27.38 39.78 40.47 0.54 0.56 0.02
7h 45.87 79.04 84.93 0.79 0.89 0.1
23h 129.07 1164.28 250.0 3.17 0.95 -2.22

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 27.38 45.87 129.07 0.74 2.24 1.49
Ebov 39.78 79.04 1164.28 0.99 4.87 3.88
Marv 40.47 84.93 250.0 1.07 2.63 1.56

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 2.68 2.83 5.45 0.08 1.02 0.95
7h 1.91 1.0 2.65 -0.93 0.47 1.41
23h 13.22 4.85 8.0 -1.45 -0.72 0.72

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 2.68 1.91 13.22 -0.49 2.3 2.79
Ebov 2.83 1.0 4.85 -1.5 0.78 2.28
Marv 5.45 2.65 8.0 -1.04 0.55 1.59