BIK
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| BIK | BCL2-Interacting Killer (Apoptosis-Inducing), NBK, BP4,NBK | BCL2-interacting killer (apoptosis-inducing) | NM_001197 |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
The protein encoded by this gene shares a critical BH3 domain with other death-promoting proteins, such as BID, BAK, BAD and BAX, that is required for its pro-apoptotic activity, and for interaction with anti-apoptotic members of the BCL2 family, and viral survival-promoting proteins. Since the activity of this protein is suppressed in the presence of survival-promoting proteins, it is suggested as a likely target for anti-apoptotic proteins.
We observed very low expression in all probes.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 3 | 2 | 2 | 2 | 2 | 11 | 2 | 3 | 2 |
Read_Max |  | R. aegyptiacus | Transcriptome | 1 | 2 | 2 | 5 | 6 | 6 | 1 | 5 | 6 |
Read_Max |  | R. aegyptiacus | Genome | 7 | 5 | 5 | 5 | 9 | 10 | 4 | 9 | 11 |
DESeq | | H. sapiens | Genome | 14.19 | 5.08 | 8.94 | 7.84 | 2.63 | 49.69 | 7.14 | 10.59 | 11.87 |
DESeq | | R. aegyptiacus | Transcriptome | 2.68 | 2.82 | 5.89 | 6.49 | 7.57 | 8.7 | 2.11 | 6.78 | 11.5 |
DESeq | | R. aegyptiacus | Genome | 30.94 | 52.02 | 72.53 | 36.54 | 78.13 | 140.98 | 58.48 | 37.27 | 99.32 |