F2RL2

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
F2RL2 B2R754, PAR3, PAR3_HUMAN,PAR3 coagulation factor II (thrombin) receptor-like 2 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

F2RL2 encodes a member of the protease-activated receptor (PAR) family which is a subfamily of the seven transmembrane G protein-coupled cell surface receptor family. The encoded protein acts as a cofactor in the thrombin-mediated cleavage and activation of the protease-activated receptor family member PAR4. The encoded protein plays an essential role in hemostasis and thrombosis. Alternate splicing results in multiple transcript variants that encode different isoforms.

For the wildtype and the Ebola cells only low expression was observed. In contrast, there was higher expression for the 7 h (3x compared to 3 h) and 23 h Marburg infected cells (148 and 193 read counts).

Show legend

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome29 30 25 33 29 16 45 150 196
Read_Max
batR. aegyptiacusTranscriptome NA NA NA NA NA NA NA NA NA
Read_Max
bat_genomeR. aegyptiacusGenome 0 0 0 0 0 0 0 1 0
DESeq
humanH. sapiensGenome 417.06 469.12 296.86 375.14 310.73 144.44 636.97 1295.95 4289.5
DESeq
batR. aegyptiacusTranscriptome NA NA NA NA NA NA NA NA NA
DESeq
bat_genomeR. aegyptiacusGenome 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.59 0.0

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 417.06 375.14 636.97 -0.15 0.61 0.76
7h 469.12 310.73 1295.95 -0.59 1.47 2.06
23h 296.86 144.44 4289.5 -1.04 3.85 4.89

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 417.06 469.12 296.86 0.17 -0.49 -0.66
Ebov 375.14 310.73 144.44 -0.27 -1.38 -1.11
Marv 636.97 1295.95 4289.5 1.02 2.75 1.73

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h NA NA NA NA NA NA
7h NA NA NA NA NA NA
23h NA NA NA NA NA NA

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock NA NA NA NA NA NA
Ebov NA NA NA NA NA NA
Marv NA NA NA NA NA NA