ITGB6

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
ITGB6 integrin, beta 6 NM_000888 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

This gene encodes a protein that is a member of the integrin superfamily. Members of this family are adhesion receptors that function in signaling from the extracellular matrix to the cell. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The encoded protein forms a dimer with an alpha v chain and this heterodimer can bind to ligands like fibronectin and transforming growth factor beta 1. Alternate splicing results in multiple transcript variants.

We observed low expression in human cells.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome26 9 24 8 23 19 31 19 29
Read_Max
batR. aegyptiacusTranscriptome 10 6 8 7 7 11 7 17 9
Read_Max
bat_genomeR. aegyptiacusGenome 12 8 12 7 7 8 6 24 15
DESeq
humanH. sapiensGenome 10.13 14.26 10.93 16.97 17.26 3.63 15.91 20.98 79.29
DESeq
batR. aegyptiacusTranscriptome 64.01 52.74 85.29 65.1 87.51 133.17 67.74 99.32 100.72
DESeq
bat_genomeR. aegyptiacusGenome 163.28 202.62 259.98 161.95 254.48 279.36 183.3 255.33 290.25

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 10.13 16.97 15.91 0.74 0.65 -0.09
7h 14.26 17.26 20.98 0.28 0.56 0.28
23h 10.93 3.63 79.29 -1.59 2.86 4.45

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 10.13 14.26 10.93 0.49 0.11 -0.38
Ebov 16.97 17.26 3.63 0.02 -2.22 -2.25
Marv 15.91 20.98 79.29 0.4 2.32 1.92

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 64.01 65.1 67.74 0.02 0.08 0.06
7h 52.74 87.51 99.32 0.73 0.91 0.18
23h 85.29 133.17 100.72 0.64 0.24 -0.4

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 64.01 52.74 85.29 -0.28 0.41 0.69
Ebov 65.1 87.51 133.17 0.43 1.03 0.61
Marv 67.74 99.32 100.72 0.55 0.57 0.02