ANXA3

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
ANXA3 Annexin A3, Lipocortin III, Inositol 1,2-Cyclic Phosphate annexin A3 NM_005139 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phopholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation.

The gene ANXA3 is very weakly expressed in human cells datasets, but moderately expressed in bat cells. For Marburg and Ebola datasets expression decreases at 7 h and increases in 23 h datasets.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome66 49 9 55 51 296 100 70 173
Read_Max
batR. aegyptiacusTranscriptome 350 375 234 319 275 415 421 286 490
Read_Max
bat_genomeR. aegyptiacusGenome 387 282 186 355 210 236 322 332 498
DESeq
humanH. sapiensGenome 325.73 292.68 64.54 411.65 274.96 1694.59 472.06 344.72 1431.95
DESeq
batR. aegyptiacusTranscriptome 1980.37 2027.87 1453.41 1667.52 2014.87 2477.54 2628.5 1795.52 2395.08
DESeq
bat_genomeR. aegyptiacusGenome 2180.27 1662.0 1508.53 2352.19 2120.65 2749.19 2749.48 1845.98 2579.71

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 325.73 411.65 472.06 0.34 0.54 0.2
7h 292.68 274.96 344.72 -0.09 0.24 0.33
23h 64.54 1694.59 1431.95 4.71 4.47 -0.24

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 325.73 292.68 64.54 -0.15 -2.34 -2.18
Ebov 411.65 274.96 1694.59 -0.58 2.04 2.62
Marv 472.06 344.72 1431.95 -0.45 1.6 2.05

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 1980.37 1667.52 2628.5 -0.25 0.41 0.66
7h 2027.87 2014.87 1795.52 -0.01 -0.18 -0.17
23h 1453.41 2477.54 2395.08 0.77 0.72 -0.05

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 1980.37 2027.87 1453.41 0.03 -0.45 -0.48
Ebov 1667.52 2014.87 2477.54 0.27 0.57 0.3
Marv 2628.5 1795.52 2395.08 -0.55 -0.13 0.42