PRSS35

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
PRSS35 MGC46520, dJ223E3.1 protease, serine, 35 NM_153362 pdf NONE

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

Homo sapiens protease, serine, 35 (PRSS35), transcript variant 1. The proteolytic activity of PRSS35 is not characterized so far, but it possess general features of serine protease, however the canonical Ser is replaced by a threonine in PRSS35~\citemiyakoshi06identification.

The gene is transcribed weakly in human cells and highly in bat cells. 23 h after infection the gene is downregulated, in human cells it is shut down completely.

Show legend

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome7 4 5 5 8 2 10 10 8
Read_Max
batR. aegyptiacusTranscriptome NA NA NA NA NA NA NA NA NA
Read_Max
bat_genomeR. aegyptiacusGenome 172 204 203 136 125 57 92 279 214
DESeq
humanH. sapiensGenome 38.55 20.38 15.89 34.08 40.83 3.63 43.11 56.16 70.59
DESeq
batR. aegyptiacusTranscriptome NA NA NA NA NA NA NA NA NA
DESeq
bat_genomeR. aegyptiacusGenome 1326.04 1840.89 2439.09 1441.73 1659.69 823.71 1322.45 1705.63 1618.2

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 38.55 34.08 43.11 -0.18 0.16 0.34
7h 20.38 40.83 56.16 1.0 1.46 0.46
23h 15.89 3.63 70.59 -2.13 2.15 4.28

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 38.55 20.38 15.89 -0.92 -1.28 -0.36
Ebov 34.08 40.83 3.63 0.26 -3.23 -3.49
Marv 43.11 56.16 70.59 0.38 0.71 0.33

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h NA NA NA NA NA NA
7h NA NA NA NA NA NA
23h NA NA NA NA NA NA

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock NA NA NA NA NA NA
Ebov NA NA NA NA NA NA
Marv NA NA NA NA NA NA