MBL2

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
MBL2 , COLEC1, HSMBPC, MBL, MBL2D, MBP, MBP-C, MBP1, MBPD,COLEC1 mannose-binding lectin (protein C) 2, soluble NM_000242 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

This gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes mannose and N-acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases.

This gene is down-regulated after 3 and 23 h, respectively in all conditions.

Show legend

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome95 51 22 80 71 6 109 70 15
Read_Max
batR. aegyptiacusTranscriptome NA NA NA NA NA NA NA NA NA
Read_Max
bat_genomeR. aegyptiacusGenome 0 0 0 0 0 0 0 0 0
DESeq
humanH. sapiensGenome 1164.96 550.71 275.02 1066.4 583.89 43.11 1014.17 439.04 177.15
DESeq
batR. aegyptiacusTranscriptome NA NA NA NA NA NA NA NA NA
DESeq
bat_genomeR. aegyptiacusGenome 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 1164.96 1066.4 1014.17 -0.13 -0.2 -0.07
7h 550.71 583.89 439.04 0.08 -0.33 -0.41
23h 275.02 43.11 177.15 -2.67 -0.63 2.04

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 1164.96 550.71 275.02 -1.08 -2.08 -1.0
Ebov 1066.4 583.89 43.11 -0.87 -4.63 -3.76
Marv 1014.17 439.04 177.15 -1.21 -2.52 -1.31

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h NA NA NA NA NA NA
7h NA NA NA NA NA NA
23h NA NA NA NA NA NA

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock NA NA NA NA NA NA
Ebov NA NA NA NA NA NA
Marv NA NA NA NA NA NA