WNT5A

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
WNT5A hWNT5A wingless-type MMTV integration site family, member 5A NM_003392 pdf NONE

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Description

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene encodes a member of the WNT family that signals through both the canonical and non-canonical WNT pathways. This protein is a ligand for the seven transmembrane receptor frizzled-5 and the tyrosine kinase orphan receptor 2. This protein plays an essential role in regulating developmental pathways during embryogenesis. This protein may also play a role in oncogenesis. Mutations in this gene are the cause of autosomal dominant Robinow syndrome.

Low expression levels in all human cells samples. %%%%%%%%%%%%%%%%%%%%%

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome4 2 2 4 3 5 3 5 6
Read_Max
batR. aegyptiacusTranscriptome 236 238 71 132 121 150 221 198 155
Read_Max
bat_genomeR. aegyptiacusGenome 0 0 0 0 0 0 0 0 0
DESeq
humanH. sapiensGenome 20.28 10.18 4.97 14.69 9.13 6.26 21.18 33.77 98.86
DESeq
batR. aegyptiacusTranscriptome 1441.0 1503.23 577.57 841.58 914.31 986.48 1588.4 880.09 868.71
DESeq
bat_genomeR. aegyptiacusGenome 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 20.28 14.69 21.18 -0.47 0.06 0.53
7h 10.18 9.13 33.77 -0.16 1.73 1.89
23h 4.97 6.26 98.86 0.33 4.31 3.98

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 20.28 10.18 4.97 -0.99 -2.03 -1.03
Ebov 14.69 9.13 6.26 -0.69 -1.23 -0.54
Marv 21.18 33.77 98.86 0.67 2.22 1.55

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 1441.0 841.58 1588.4 -0.78 0.14 0.92
7h 1503.23 914.31 880.09 -0.72 -0.77 -0.06
23h 577.57 986.48 868.71 0.77 0.59 -0.18

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 1441.0 1503.23 577.57 0.06 -1.32 -1.38
Ebov 841.58 914.31 986.48 0.12 0.23 0.11
Marv 1588.4 880.09 868.71 -0.85 -0.87 -0.02