MYEF2

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
MYEF2 FLJ11213, HsT18564, KIAA1341, MEF-2,MEF-2, FLJ11213 myelin expression factor 2 NM_016132 pdf

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Description

MYEF2 encodes for myelin expression factor 2 and is a transcriptional repressor of the myelin basic protein gene (MBP). It can bind to the proximal MB1 element 5'-TTGTCC-3' of the MBP promoter. Its binding to MB1 and function are inhibited by PURA.

It is not expressed in human cells or only at very low level but it is constantly expressed at a moderate level in bat cells.

Show legend

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome2 2 4 2 4 15 4 3 3
Read_Max
batR. aegyptiacusTranscriptome 385 232 188 290 239 296 233 339 243
Read_Max
bat_genomeR. aegyptiacusGenome 453 321 170 323 212 182 225 433 283
DESeq
humanH. sapiensGenome 11.15 8.14 16.89 4.42 14.01 79.96 16.79 12.99 21.66
DESeq
batR. aegyptiacusTranscriptome 1752.69 1345.29 1321.48 1569.54 1527.56 1642.19 1586.18 1550.97 1258.83
DESeq
bat_genomeR. aegyptiacusGenome 5562.83 5133.85 3340.64 4813.98 5358.56 5810.38 5906.04 5085.16 4000.98

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 11.15 4.42 16.79 -1.33 0.59 1.93
7h 8.14 14.01 12.99 0.78 0.67 -0.11
23h 16.89 79.96 21.66 2.24 0.36 -1.88

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 11.15 8.14 16.89 -0.45 0.6 1.05
Ebov 4.42 14.01 79.96 1.66 4.18 2.51
Marv 16.79 12.99 21.66 -0.37 0.37 0.74

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 1752.69 1569.54 1586.18 -0.16 -0.14 0.02
7h 1345.29 1527.56 1550.97 0.18 0.21 0.02
23h 1321.48 1642.19 1258.83 0.31 -0.07 -0.38

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 1752.69 1345.29 1321.48 -0.38 -0.41 -0.03
Ebov 1569.54 1527.56 1642.19 -0.04 0.07 0.1
Marv 1586.18 1550.97 1258.83 -0.03 -0.33 -0.3