NUDT7

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

The protein encoded by this gene is a member of the Nudix hydrolase family. Nudix hydrolases eliminate potentially toxic nucleotide metabolites from the cell and regulate the concentrations and availability of many different nucleotide substrates, cofactors, and signaling molecules.

This gene is upregulated in Ebola and Marburg infected human cells cells after 7 h but not after 23 h. No credible homolog in bat cells was found.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome5 5 5 10 15 3 6 16 5
Read_Max
batR. aegyptiacusTranscriptome 40 40 45 34 35 32 26 41 47
Read_Max
bat_genomeR. aegyptiacusGenome 40 36 39 35 29 17 27 55 49
DESeq
humanH. sapiensGenome 40.58 61.17 59.58 61.46 61.97 3.63 49.25 53.76 42.32
DESeq
batR. aegyptiacusTranscriptome 90.05 99.03 156.14 112.71 141.17 119.05 100.0 141.46 132.21
DESeq
bat_genomeR. aegyptiacusGenome 133.21 158.81 194.15 150.1 188.63 152.73 124.82 191.1 163.53

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 40.58 61.46 49.25 0.6 0.28 -0.32
7h 61.17 61.97 53.76 0.02 -0.19 -0.21
23h 59.58 3.63 42.32 -4.04 -0.49 3.54

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 40.58 61.17 59.58 0.59 0.55 -0.04
Ebov 61.46 61.97 3.63 0.01 -4.08 -4.09
Marv 49.25 53.76 42.32 0.13 -0.22 -0.35

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 90.05 112.71 100.0 0.32 0.15 -0.17
7h 99.03 141.17 141.46 0.51 0.51 0.0
23h 156.14 119.05 132.21 -0.39 -0.24 0.15

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 90.05 99.03 156.14 0.14 0.79 0.66
Ebov 112.71 141.17 119.05 0.32 0.08 -0.25
Marv 100.0 141.46 132.21 0.5 0.4 -0.1