CXCL1
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| CXCL1 | CXCL1, FSP, GRO1, GROa, MGSA, MGSA-a, NAP-3, SCYB1,SCYB1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |  |
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NONE |
Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4.
Overall expression is low across all samples.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 10 | 2 | 0 | 9 | 3 | 26 | 11 | 5 | 4 |
Read_Max |  | R. aegyptiacus | Transcriptome | NA | NA | NA | NA | NA | NA | NA | NA | NA |
Read_Max |  | R. aegyptiacus | Genome | NA | NA | NA | NA | NA | NA | NA | NA | NA |
DESeq | | H. sapiens | Genome | 17.24 | 5.08 | 1.0 | 30.66 | 5.06 | 89.17 | 39.6 | 8.99 | 8.61 |
DESeq | | R. aegyptiacus | Transcriptome | NA | NA | NA | NA | NA | NA | NA | NA | NA |
DESeq | | R. aegyptiacus | Genome | NA | NA | NA | NA | NA | NA | NA | NA | NA |