B3GALT2

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
B3GALT2 B2RAB1, B3GT2_HUMAN, NM_003783, NP_003774, O43825, Q9BZQ9,beta3Gal-T2 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2 NM_003783 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

B3GALT2 is a member of the beta-1,3-galactosyltransferase (beta3GalT)gene family. This family encodes type II membrane-bound glycoproteins withdiverse enzymatic functions using different donor substrates (UDP-galactoseand UDP-N-acetylglucosamine) and different acceptor sugars(N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genesare distantly related to the Drosophila Brainiac gene and have the proteincoding sequence contained in a single exon. The beta3GalT proteins alsocontain conserved sequences not found in the beta4GalT or alpha3GalTproteins. The carbohydrate chains synthesized by these enzymes aredesignated as type 1, whereas beta4GalT enzymes synthesize type 2carbohydrate chains. The ratio of type 1:type 2 chains changes duringembryogenesis. By sequence similarity, the beta3GalT genes fall into atleast two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3,beta3GalT5). This gene encodes a protein that functions in N-linkedglycoprotein glycosylation and shows strict donor substrate specificity forUDP-galactose.

Only very few hits mapped to the locus of this gene. The maximum were 39reads in the Ebola 23 h probe in human cells.

Show legend

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome8 8 7 7 7 42 8 7 3
Read_Max
batR. aegyptiacusTranscriptome NA NA NA NA NA NA NA NA NA
Read_Max
bat_genomeR. aegyptiacusGenome 262 138 81 174 94 83 105 177 155
DESeq
humanH. sapiensGenome 48.69 51.99 44.68 44.35 51.4 445.78 60.65 39.37 21.66
DESeq
batR. aegyptiacusTranscriptome NA NA NA NA NA NA NA NA NA
DESeq
bat_genomeR. aegyptiacusGenome 5.16 9.13 13.39 4.94 6.7 5.22 2.25 6.34 3.42

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 48.69 44.35 60.65 -0.13 0.32 0.45
7h 51.99 51.4 39.37 -0.02 -0.4 -0.38
23h 44.68 445.78 21.66 3.32 -1.04 -4.36

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 48.69 51.99 44.68 0.09 -0.12 -0.22
Ebov 44.35 51.4 445.78 0.21 3.33 3.12
Marv 60.65 39.37 21.66 -0.62 -1.49 -0.86

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h NA NA NA NA NA NA
7h NA NA NA NA NA NA
23h NA NA NA NA NA NA

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock NA NA NA NA NA NA
Ebov NA NA NA NA NA NA
Marv NA NA NA NA NA NA