CYP7B1
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| CYP7B1 | SPG5A | cytochrome P450, family 7, subfamily B, polypeptide 1 |  |
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NONE |
Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis.
Almost no expression in human cells but constant low expression in bat cells.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 10 | 10 | 24 | 12 | 25 | 44 | 22 | 13 | 9 |
Read_Max |  | R. aegyptiacus | Transcriptome | 140 | 107 | 40 | 99 | 79 | 51 | 93 | 88 | 49 |
Read_Max |  | R. aegyptiacus | Genome | NA | NA | NA | NA | NA | NA | NA | NA | NA |
DESeq | | H. sapiens | Genome | 28.4 | 20.38 | 27.81 | 28.38 | 25.39 | 2.32 | 31.7 | 22.58 | 5.35 |
DESeq | | R. aegyptiacus | Transcriptome | 580.7 | 515.66 | 323.49 | 593.44 | 655.86 | 352.59 | 669.56 | 533.9 | 267.79 |
DESeq | | R. aegyptiacus | Genome | NA | NA | NA | NA | NA | NA | NA | NA | NA |