CDKL2

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
CDKL2 P56, KKIAMRE cyclin-dependent kinase-like 2 (CDC2-related kinase) NM_003948 pdf NONE

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

Homo sapiens cyclin-dependent kinase-like 2 (CDC2-related kinase) (CDKL2), mRNA. This gene product is a member of a large family of CDC2-related serine/threonine protein kinases. It accumulates primarily in the cytoplasm, with lower levels in the nucleus.

No expression detectable over all human samples. But RAE homolog sequence shows slight expressen with 5 fold increased upregulation in RAE ebola 23h.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome3 2 3 3 4 8 2 2 5
Read_Max
batR. aegyptiacusTranscriptome 14 9 9 13 9 26 15 11 13
Read_Max
bat_genomeR. aegyptiacusGenome 707 528 286 417 384 253 412 745 516
DESeq
humanH. sapiensGenome 3.03 10.18 6.96 10.13 9.13 122.06 4.51 7.39 14.05
DESeq
batR. aegyptiacusTranscriptome 100.98 56.37 76.74 66.93 66.71 199.89 100.0 71.23 66.6
DESeq
bat_genomeR. aegyptiacusGenome 6790.04 6276.53 5343.46 5588.17 6557.29 7195.42 7742.4 6738.45 5901.73

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 3.03 10.13 4.51 1.74 0.57 -1.17
7h 10.18 9.13 7.39 -0.16 -0.46 -0.31
23h 6.96 122.06 14.05 4.13 1.01 -3.12

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 3.03 10.18 6.96 1.75 1.2 -0.55
Ebov 10.13 9.13 122.06 -0.15 3.59 3.74
Marv 4.51 7.39 14.05 0.71 1.64 0.93

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 100.98 66.93 100.0 -0.59 -0.01 0.58
7h 56.37 66.71 71.23 0.24 0.34 0.09
23h 76.74 199.89 66.6 1.38 -0.2 -1.59

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 100.98 56.37 76.74 -0.84 -0.4 0.45
Ebov 66.93 66.71 199.89 -0.0 1.58 1.58
Marv 100.0 71.23 66.6 -0.49 -0.59 -0.1