EMP3

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
EMP3	EMP3_HUMAN, NM_001425, NP_001416, P54852, Q6FH01, YMP,YMP	epithelial membrane protein 3	NM_001425	pdf

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Description

Homo sapiens epithelial membrane protein 3 (EMP3) mRNA is probably involved in cell proliferation and cell-cell interactions.

In hg19 samples, the expression level is very low, but shows during marburg infection a slight upregulation. In contrast, the RAE sample homologs are highly expressed. For RAE MOCK and ebola infected samples the amount of transcripts decreases two fold within the first 7h. For marbug infected samples no differential expression could be observed.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source	Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max	H. sapiens	Genome	7	2	6	7	5	23	12	5	24
Read_Max	R. aegyptiacus	Transcriptome	198	208	97	99	96	112	126	117	134
Read_Max	R. aegyptiacus	Genome	228	115	96	182	77	67	112	126	169
DESeq	H. sapiens	Genome	23.33	5.08	12.91	4.42	10.76	66.8	20.3	12.19	85.81
DESeq	R. aegyptiacus	Transcriptome	458.88	537.44	323.49	284.86	303.24	330.78	427.05	279.43	372.75
DESeq	R. aegyptiacus	Genome	590.4	393.37	434.04	686.3	415.2	520.86	580.26	380.61	547.11

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	23.33	4.42	20.3	-2.4	-0.2	2.2
7h	5.08	10.76	12.19	1.08	1.26	0.18
23h	12.91	66.8	85.81	2.37	2.73	0.36

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	23.33	5.08	12.91	-2.2	-0.85	1.35
Ebov	4.42	10.76	66.8	1.28	3.92	2.63
Marv	20.3	12.19	85.81	-0.74	2.08	2.82

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	458.88	284.86	427.05	-0.69	-0.1	0.58
7h	537.44	303.24	279.43	-0.83	-0.94	-0.12
23h	323.49	330.78	372.75	0.03	0.2	0.17

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	458.88	537.44	323.49	0.23	-0.5	-0.73
Ebov	284.86	303.24	330.78	0.09	0.22	0.13
Marv	427.05	279.43	372.75	-0.61	-0.2	0.42

Differential transcriptional responses to Ebola and Marburg virus infection in cells from bats and humans

Supplemental Material