TTBK1

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
TTBK1	BDTK,KIAA1855	tau tubulin kinase 1		pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

Serine/threonine kinase which is able to phosphorylate TAU on serine, threonine and tyrosine residues. Induces aggregation of TAU (UniProt)

We observed no differential expression and very low expression level.

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source		Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max		H. sapiens	Genome	6	9	5	3	5	2	4	6	4
Read_Max		R. aegyptiacus	Transcriptome	NA	NA	NA	NA	NA	NA	NA	NA	NA
Read_Max		R. aegyptiacus	Genome	2	1	2	0	1	2	0	0	2
DESeq		H. sapiens	Genome	42.61	65.25	46.67	20.39	44.9	3.63	36.97	36.97	26.01
DESeq		R. aegyptiacus	Transcriptome	NA	NA	NA	NA	NA	NA	NA	NA	NA
DESeq		R. aegyptiacus	Genome	1.72	2.74	5.58	0.0	2.23	2.61	0.0	0.0	1.71

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	42.61	20.39	36.97	-1.06	-0.2	0.86
7h	65.25	44.9	36.97	-0.54	-0.82	-0.28
23h	46.67	3.63	26.01	-3.68	-0.84	2.84

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	42.61	65.25	46.67	0.61	0.13	-0.48
Ebov	20.39	44.9	3.63	1.14	-2.49	-3.63
Marv	36.97	36.97	26.01	0.0	-0.51	-0.51

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	NA	NA	NA	NA	NA	NA
7h	NA	NA	NA	NA	NA	NA
23h	NA	NA	NA	NA	NA	NA

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	NA	NA	NA	NA	NA	NA
Ebov	NA	NA	NA	NA	NA	NA
Marv	NA	NA	NA	NA	NA	NA