LIPH

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
LIPH	AH, ARWH2, HYPT7, LAH2, LPDLR, PLA1B, mPA-PLA1,mPA-PLA1, mPA-PLA1alpha	lipase, member H		pdf

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Description

The lipase, member H (EC:2.7.11.30) gene is involved in the lipid catabolic process. Hydrolyzes specifically phosphatidic acid (PA) to produce 2-acyl lysophosphatidic acid (LPA; a potent bioactive lipid mediator) and fatty acid. Does not hydrolyze other phospholipids, like phosphatidylserine (PS), phosphatidylcholine (PC) and phosphatidylethanolamine (PE) or triacylglycerol (TG).

It does not present a particularly interesting differential expression pattern in the samples analyzed.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source	Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max	H. sapiens	Genome	7	4	5	9	7	5	3	10	14
Read_Max	R. aegyptiacus	Transcriptome	5	4	9	4	5	14	2	6	14
Read_Max	R. aegyptiacus	Genome	7	9	4	4	4	11	2	6	15
DESeq	H. sapiens	Genome	32.46	29.56	48.66	50.05	41.65	8.9	20.3	43.37	128.22
DESeq	R. aegyptiacus	Transcriptome	16.12	7.35	21.77	10.16	16.33	52.33	5.45	23.31	52.61
DESeq	R. aegyptiacus	Genome	33.52	32.86	34.59	10.86	29.02	130.54	13.49	36.48	126.72

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	32.46	50.05	20.3	0.62	-0.68	-1.3
7h	29.56	41.65	43.37	0.49	0.55	0.06
23h	48.66	8.9	128.22	-2.45	1.4	3.85

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	32.46	29.56	48.66	-0.14	0.58	0.72
Ebov	50.05	41.65	8.9	-0.27	-2.49	-2.23
Marv	20.3	43.37	128.22	1.1	2.66	1.56

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	16.12	10.16	5.45	-0.67	-1.56	-0.9
7h	7.35	16.33	23.31	1.15	1.67	0.51
23h	21.77	52.33	52.61	1.27	1.27	0.01

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	16.12	7.35	21.77	-1.13	0.43	1.57
Ebov	10.16	16.33	52.33	0.68	2.36	1.68
Marv	5.45	23.31	52.61	2.1	3.27	1.17

Differential transcriptional responses to Ebola and Marburg virus infection in cells from bats and humans

Supplemental Material