UBASH3B

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
UBASH3B STS-1, STS1, TULA-2, p70,KIAA1959, STS-1, TULA2 ubiquitin associated and SH3 domain containing B NM_032873 pdf NONE

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

This gene encodes a protein that contains a ubiquitin associated domain at the N-terminus, an SH3 domain, and a C-terminal domain with similarities to the catalytic motif of phosphoglycerate mutase. The encoded protein was found to inhibit endocytosis of epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor.

This gene is up-regulated in Ebola infected samples at 23 h in both organisms. %%%%%%%%%%%%%%%%%%%%%

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome9 11 4 10 13 57 12 20 22
Read_Max
batR. aegyptiacusTranscriptome 84 74 43 64 65 115 71 78 122
Read_Max
bat_genomeR. aegyptiacusGenome 94 66 39 59 43 70 52 90 124
DESeq
humanH. sapiensGenome 129.88 144.8 58.58 162.98 100.18 905.04 119.42 144.88 248.92
DESeq
batR. aegyptiacusTranscriptome 878.95 734.41 556.8 682.26 677.77 1408.65 778.57 694.19 1029.66
DESeq
bat_genomeR. aegyptiacusGenome 1798.7 1580.77 1487.33 1558.25 1523.52 3442.37 1963.43 1506.6 2499.22

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 129.88 162.98 119.42 0.33 -0.12 -0.45
7h 144.8 100.18 144.88 -0.53 0.0 0.53
23h 58.58 905.04 248.92 3.95 2.09 -1.86

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 129.88 144.8 58.58 0.16 -1.15 -1.31
Ebov 162.98 100.18 905.04 -0.7 2.47 3.18
Marv 119.42 144.88 248.92 0.28 1.06 0.78

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 878.95 682.26 778.57 -0.37 -0.17 0.19
7h 734.41 677.77 694.19 -0.12 -0.08 0.03
23h 556.8 1408.65 1029.66 1.34 0.89 -0.45

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 878.95 734.41 556.8 -0.26 -0.66 -0.4
Ebov 682.26 677.77 1408.65 -0.01 1.05 1.06
Marv 778.57 694.19 1029.66 -0.17 0.4 0.57