NEDD9
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| NEDD9 | , CAS-L, CAS2, CASL, CASS2, HEF1,HEF1 | neural precursor cell expressed, developmentally down-regulated 9 | NM_006403 |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. Alternative splicing results in multiple transcript variants.
Strong induction of NEDD9 in Ebola infected human cells cells at 23 h post infection. No induction of the homolog bat cells gene.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 17 | 14 | 25 | 16 | 16 | 198 | 20 | 20 | 19 |
Read_Max |  | R. aegyptiacus | Transcriptome | 448 | 343 | 196 | 182 | 186 | 289 | 256 | 199 | 259 |
Read_Max |  | R. aegyptiacus | Genome | 446 | 193 | 215 | 311 | 155 | 177 | 274 | 277 | 389 |
DESeq | | H. sapiens | Genome | 273.98 | 175.4 | 293.88 | 255.37 | 183.1 | 2746.01 | 262.41 | 201.64 | 276.1 |
DESeq | | R. aegyptiacus | Transcriptome | 4237.83 | 4110.11 | 3294.26 | 2339.62 | 2578.84 | 4013.51 | 3905.55 | 2339.17 | 3006.5 |
DESeq | | R. aegyptiacus | Genome | 5503.53 | 3237.29 | 4262.27 | 5599.03 | 3559.35 | 5504.91 | 5638.4 | 3170.99 | 4189.35 |