ASAH2
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| ASAH2 | N-CDase, Acylsphingosine deacylase 2, BCDase, LCDase, hCD, N-acylsphingosine amidohydrolase 2, Non-lysosomal ceramidase | N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2 | NM_019893 |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
Ceramidases (EC 3.5.1.23), such as ASAH2, catalyze hydrolysis of the N-acyl linkage of ceramide, a second messenger in a variety of cellular events, to produce sphingosine. Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form functions as an intra- and intercellular second messenger.
The gene is equally expressed in all human cells samples, but could not be detected in the bat cells transcriptome.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 80 | 62 | 60 | 72 | 80 | 58 | 87 | 90 | 65 |
Read_Max |  | R. aegyptiacus | Transcriptome | NA | NA | NA | NA | NA | NA | NA | NA | NA |
Read_Max |  | R. aegyptiacus | Genome | 2 | 2 | 2 | 3 | 4 | 2 | 1 | 3 | 2 |
DESeq | | H. sapiens | Genome | 58.84 | 91.77 | 71.49 | 66.02 | 79.86 | 8.9 | 65.91 | 120.1 | 116.26 |
DESeq | | R. aegyptiacus | Transcriptome | NA | NA | NA | NA | NA | NA | NA | NA | NA |
DESeq | | R. aegyptiacus | Genome | 12.89 | 8.21 | 8.93 | 7.9 | 11.16 | 33.94 | 4.5 | 5.55 | 7.71 |