SAMD4A

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
SAMD4A DKFZP434H0350, hSmaug1, KIAA1053, SAMD4, Smaug, SMG, SMGA,KIAA1053, DKFZP434H0350 sterile alpha motif domain containing 4A NM_015589 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

Sterile alpha motifs (SAMs) in proteins such as SAMD4A are part of an RNA-binding domain that functions as a posttranscriptional regulator by binding to an RNA sequence motif known as the Smaug recognition element, which was named after the Drosophila Smaug protein.

General low expression in human cells but upregulated after 23 h of Ebola virus infection. In bat cells it is constantely expressed at a distinct higher level.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome43 21 13 25 22 213 35 26 31
Read_Max
batR. aegyptiacusTranscriptome 380 310 352 387 403 526 305 427 429
Read_Max
bat_genomeR. aegyptiacusGenome 723 505 445 423 426 489 352 670 755
DESeq
humanH. sapiensGenome 838.2 417.11 364.37 696.82 413.98 5029.14 818.55 461.43 798.03
DESeq
batR. aegyptiacusTranscriptome 4802.4 4154.59 4550.0 5071.06 5086.6 7399.83 4343.83 4356.77 4434.02
DESeq
bat_genomeR. aegyptiacusGenome 12647.64 13529.64 14495.07 11435.06 14540.99 21920.44 12820.79 12541.23 13556.08

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 838.2 696.82 818.55 -0.27 -0.03 0.23
7h 417.11 413.98 461.43 -0.01 0.15 0.16
23h 364.37 5029.14 798.03 3.79 1.13 -2.66

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 838.2 417.11 364.37 -1.01 -1.2 -0.2
Ebov 696.82 413.98 5029.14 -0.75 2.85 3.6
Marv 818.55 461.43 798.03 -0.83 -0.04 0.79

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 4802.4 5071.06 4343.83 0.08 -0.14 -0.22
7h 4154.59 5086.6 4356.77 0.29 0.07 -0.22
23h 4550.0 7399.83 4434.02 0.7 -0.04 -0.74

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 4802.4 4154.59 4550.0 -0.21 -0.08 0.13
Ebov 5071.06 5086.6 7399.83 0.0 0.55 0.54
Marv 4343.83 4356.77 4434.02 0.0 0.03 0.03