PTGR1
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| PTGR1 | LTB4DH, ZADH3,ZADH3 | prostaglandin reductase 1 |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
This gene encodes an enzyme that is involved in the inactivation of the chemotactic factor, leukotriene B4. The encoded protein specifically catalyzes the NADP+ dependent conversion of leukotriene B4 to 12-oxo-leukotriene B4. A pseudogene of this gene is found on chromosome 1. Alternative splicing results in multiple transcript variants.
It is upregulated in human cells and bat cells after Marburg virus infection.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 248 | 206 | 177 | 235 | 253 | 119 | 359 | 702 | 846 |
Read_Max |  | R. aegyptiacus | Transcriptome | 47 | 50 | 96 | 69 | 58 | 86 | 53 | 130 | 186 |
Read_Max |  | R. aegyptiacus | Genome | 52 | 71 | 82 | 48 | 46 | 47 | 44 | 153 | 200 |
DESeq | | H. sapiens | Genome | 1848.93 | 1966.3 | 1552.78 | 1994.91 | 1932.57 | 814.24 | 2639.63 | 4897.82 | 9779.51 |
DESeq | | R. aegyptiacus | Transcriptome | 253.88 | 268.77 | 731.48 | 360.86 | 333.91 | 507.86 | 300.24 | 433.11 | 868.71 |
DESeq | | R. aegyptiacus | Genome | 300.79 | 407.06 | 756.5 | 336.73 | 426.36 | 535.22 | 335.11 | 463.08 | 970.07 |