NUAK2

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
NUAK2 SNARK, FLJ90349 NUAK family, SNF1-like kinase, 2 NM_030952 pdf

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Description

Homo sapiens NUAK family, SNF1-like kinase, 2 (NUAK2), mRNA.

This gene shows opposite expression changes in bat cells after Marburg (upregulation) and Ebola (downregulation) infection. In human cells, it is slightly downregulated after 7 h Ebola infection, but highly upregulated in after 23 h.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome21 22 11 26 14 146 40 28 16
Read_Max
batR. aegyptiacusTranscriptome 121 118 114 96 79 79 98 128 176
Read_Max
bat_genomeR. aegyptiacusGenome 130 93 92 108 66 43 84 148 166
DESeq
humanH. sapiensGenome 407.93 251.89 175.74 360.32 183.91 2082.79 458.9 306.35 302.2
DESeq
batR. aegyptiacusTranscriptome 569.78 661.8 795.0 655.7 567.16 438.56 646.2 707.41 912.45
DESeq
bat_genomeR. aegyptiacusGenome 1191.97 1180.1 1569.9 1265.95 1147.39 950.34 1196.5 1238.58 1733.79

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 407.93 360.32 458.9 -0.18 0.17 0.35
7h 251.89 183.91 306.35 -0.45 0.28 0.74
23h 175.74 2082.79 302.2 3.57 0.78 -2.78

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 407.93 251.89 175.74 -0.7 -1.21 -0.52
Ebov 360.32 183.91 2082.79 -0.97 2.53 3.5
Marv 458.9 306.35 302.2 -0.58 -0.6 -0.02

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 569.78 655.7 646.2 0.2 0.18 -0.02
7h 661.8 567.16 707.41 -0.22 0.1 0.32
23h 795.0 438.56 912.45 -0.86 0.2 1.06

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 569.78 661.8 795.0 0.22 0.48 0.26
Ebov 655.7 567.16 438.56 -0.21 -0.58 -0.37
Marv 646.2 707.41 912.45 0.13 0.5 0.37