SYNGAP1
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| SYNGAP1 | upstream region: XLOC_015180, ,SYNGAP, RASA5, KIAA1938 | synaptic Ras GTPase activating protein 1 | XM_166407 |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
The protein encoded by this gene is a major component of the postsynaptic density (PSD), a group of proteins found associated with NMDA receptors at synapses. The encoded protein is phosphorylated by calmodulin-dependent protein kinase II and dephosphorylated by NMDA receptor activation. Defects in this gene are a cause of mental retardation autosomal dominant type 5 (MRD5).
The gene is not present in human cells cells except after 23 h of Ebola infection and on the other hand is moderately expressed in all bat cells samples.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 7 | 6 | 9 | 8 | 10 | 58 | 11 | 9 | 10 |
Read_Max |  | R. aegyptiacus | Transcriptome | 26 | 35 | 47 | 49 | 29 | 43 | 33 | 37 | 67 |
Read_Max |  | R. aegyptiacus | Genome | 40 | 68 | 40 | 37 | 38 | 30 | 31 | 55 | 79 |
DESeq | | H. sapiens | Genome | 152.2 | 171.32 | 200.56 | 153.85 | 183.1 | 1428.78 | 151.88 | 200.04 | 215.21 |
DESeq | | R. aegyptiacus | Transcriptome | 241.28 | 238.81 | 457.85 | 360.86 | 286.82 | 396.22 | 216.81 | 313.31 | 446.23 |
DESeq | | R. aegyptiacus | Genome | 657.43 | 1059.63 | 1299.88 | 744.56 | 945.37 | 1082.18 | 564.52 | 945.98 | 1139.59 |