GPAM
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| GPAM | KIAA1560, MGC26846, GPAT1 | glycerol-3-phosphate acyltransferase, mitochondrial | NM_020918 |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
This gene encodes a mitochondrial enzyme which prefers saturated fatty acids as its substrate for the synthesis of glycerolipids. This metabolic pathway's first step is catalyzed by the encoded enzyme. Two forms for this enzyme exist, one in the mitochondria and one in the endoplasmic reticulum. Two alternatively spliced transcript variants have been described for this gene.
This gene was expressed in all probes. For the 23 h probes, a slight upregulation was observed in the human cells wildtype probe. All other 23 h probes (both human cells and bat cells) showed a slight downregulation. However, a huge downregulation (almost 8x) was observed for the 23 h infected Ebola probe in human cells.
We also found two alternatively spliced exons in the 3'UTR that are not part of the RefSeq-Annotation.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 382 | 337 | 463 | 334 | 570 | 75 | 355 | 394 | 253 |
Read_Max |  | R. aegyptiacus | Transcriptome | 119 | 122 | 74 | 123 | 112 | 103 | 112 | 134 | 84 |
Read_Max |  | R. aegyptiacus | Genome | 123 | 125 | 57 | 123 | 85 | 55 | 95 | 155 | 93 |
DESeq | | H. sapiens | Genome | 8091.9 | 7260.46 | 8294.06 | 7491.87 | 8258.14 | 1036.63 | 6544.95 | 6619.62 | 5536.68 |
DESeq | | R. aegyptiacus | Transcriptome | 1335.14 | 1209.14 | 1011.21 | 1479.8 | 1441.04 | 955.69 | 1430.44 | 1420.43 | 821.48 |
DESeq | | R. aegyptiacus | Genome | 2204.34 | 2336.47 | 1490.68 | 2118.15 | 2266.87 | 1522.11 | 2282.8 | 2187.74 | 1328.81 |