MBNL2
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| MBNL2 | MBLL, MBLL39, PRO2032 | muscleblind-like splicing regulator 2 | NM_144778 |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
This gene is a member of the muscleblind protein family which was initially described in Drosophila melanogaster. This gene encodes a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Expressed in human as well as rae. Highly upregulated in EBOV 23h.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 72 | 71 | 69 | 49 | 91 | 327 | 60 | 81 | 106 |
Read_Max |  | R. aegyptiacus | Transcriptome | 157 | 119 | 71 | 98 | 65 | 107 | 100 | 82 | 78 |
Read_Max |  | R. aegyptiacus | Genome | 185 | 167 | 83 | 122 | 80 | 86 | 108 | 173 | 131 |
DESeq | | H. sapiens | Genome | 1223.82 | 1179.97 | 1003.75 | 890.73 | 1020.44 | 6096.35 | 911.54 | 945.03 | 1582.0 |
DESeq | | R. aegyptiacus | Transcriptome | 793.25 | 647.28 | 454.19 | 511.03 | 384.28 | 530.95 | 652.87 | 384.36 | 306.27 |
DESeq | | R. aegyptiacus | Genome | 2402.85 | 1949.49 | 1728.34 | 2025.33 | 1703.22 | 2072.99 | 2291.8 | 1669.15 | 1315.97 |