SULT1C4

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
SULT1C4 SULT1C4, SULT1C, SULT1C2,SULT1C sulfotransferase family, cytosolic, 1C, member 4 NM_006588 pdf NONE

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a protein that belongs to the SULT1 subfamily, responsible for transferring a sulfo moiety from PAPS to phenol-containing compounds.

This gene is upregulated in Ebola-infected cells after 23 h. Moreover, there is an alternative splicing event with the upstream SULT1C2P1 gene, where the first exon is skipped.

Show legend

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome106 97 70 90 133 765 132 128 151
Read_Max
batR. aegyptiacusTranscriptome NA NA NA 2 NA NA NA NA 1
Read_Max
bat_genomeR. aegyptiacusGenome NA NA NA NA NA NA NA NA NA
DESeq
humanH. sapiensGenome 933.59 842.4 713.85 853.09 952.15 4673.84 945.75 915.46 1503.71
DESeq
batR. aegyptiacusTranscriptome 1.0 1.0 1.0 3.75 1.0 1.0 1.0 1.0 1.87
DESeq
bat_genomeR. aegyptiacusGenome NA NA NA NA NA NA NA NA NA

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 933.59 853.09 945.75 -0.13 0.02 0.15
7h 842.4 952.15 915.46 0.18 0.12 -0.06
23h 713.85 4673.84 1503.71 2.71 1.07 -1.64

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 933.59 842.4 713.85 -0.15 -0.39 -0.24
Ebov 853.09 952.15 4673.84 0.16 2.45 2.3
Marv 945.75 915.46 1503.71 -0.05 0.67 0.72

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 1.0 3.75 1.0 1.91 0.0 -1.91
7h 1.0 1.0 1.0 0.0 0.0 0.0
23h 1.0 1.0 1.87 0.0 0.9 0.9

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 1.0 1.0 1.0 0.0 0.0 0.0
Ebov 3.75 1.0 1.0 -1.91 -1.91 0.0
Marv 1.0 1.0 1.87 0.0 0.9 0.9