STX3

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
STX3 STX3A syntaxin 3 NM_004177 pdf

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Description

The gene is a member of the syntaxin family. The encoded protein is targeted to the apical membrane of epithelial cells where it forms clusters and is important in establishing and maintaining polarity necessary for protein trafficking involving vesicle fusion and exocytosis. Gene is expressed in bat and human and upregulated in both upon EBOV infection. There is a pseudogene with wrong mapping in an intron.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome565 508 425 564 627 1565 726 823 534
Read_Max
batR. aegyptiacusTranscriptome 27 16 32 20 19 63 19 46 42
Read_Max
bat_genomeR. aegyptiacusGenome 31 25 34 22 19 38 24 63 49
DESeq
humanH. sapiensGenome 3153.94 3224.82 2774.95 3385.41 3541.4 16709.26 3433.5 3637.25 7874.48
DESeq
batR. aegyptiacusTranscriptome 101.82 78.15 163.46 104.47 115.98 311.53 104.45 152.2 206.56
DESeq
bat_genomeR. aegyptiacusGenome 276.72 364.16 470.86 303.16 376.14 808.05 304.75 440.09 562.52

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 3153.94 3385.41 3433.5 0.1 0.12 0.02
7h 3224.82 3541.4 3637.25 0.14 0.17 0.04
23h 2774.95 16709.26 7874.48 2.59 1.5 -1.09

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 3153.94 3224.82 2774.95 0.03 -0.18 -0.22
Ebov 3385.41 3541.4 16709.26 0.06 2.3 2.24
Marv 3433.5 3637.25 7874.48 0.08 1.2 1.11

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 101.82 104.47 104.45 0.04 0.04 -0.0
7h 78.15 115.98 152.2 0.57 0.96 0.39
23h 163.46 311.53 206.56 0.93 0.34 -0.59

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 101.82 78.15 163.46 -0.38 0.68 1.06
Ebov 104.47 115.98 311.53 0.15 1.58 1.43
Marv 104.45 152.2 206.56 0.54 0.98 0.44