FST
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| FST | FS | follistatin | NM_013409 |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. In a study in which 37 candidate genes were tested for linkage and association with polycystic ovary syndrome (PCOS) or hyperandrogenemia in 150 families, evidence was found for linkage between PCOS and follistatin.
Moderate expression in human cells with downregulation after 23 h of Ebola infection. In bat cells very low expression in all investigated conditions.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 447 | 468 | 348 | 443 | 585 | 197 | 678 | 875 | 693 |
Read_Max |  | R. aegyptiacus | Transcriptome | 43 | 38 | 36 | 39 | 24 | 14 | 30 | 31 | 50 |
Read_Max |  | R. aegyptiacus | Genome | 42 | 38 | 37 | 32 | 18 | 11 | 26 | 38 | 62 |
DESeq | | H. sapiens | Genome | 4269.19 | 3951.99 | 3483.83 | 4174.76 | 4364.11 | 1214.28 | 5004.58 | 5630.83 | 7190.54 |
DESeq | | R. aegyptiacus | Transcriptome | 156.43 | 156.21 | 308.83 | 190.54 | 156.5 | 65.16 | 150.06 | 143.93 | 257.29 |
DESeq | | R. aegyptiacus | Genome | 203.68 | 277.46 | 455.24 | 228.11 | 225.46 | 122.71 | 236.15 | 230.75 | 420.39 |