FAM53C

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
FAM53C B2RDJ5, C5orf6, D3DQB9, FA53C_HUMAN, NM_001135647, NP_057689, Q9NYF3 family with sequence similarity 53, member C NM_016605 pdf

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Description

Homo sapiens family with sequence similarity 53, member C (FAM53C), transcript variant 1, mRNA. Experimental validated, but exact function unclear, belongs to Acetylation- and Phosphoprotein.

It is strongly expressed during Ebola infection in human cells after 23 h. It also shows expression over all introns, which are upregulated for Ebola samples, while the third intron is even downregulated in human cells Marburg infected samples. In comparison, the homolog sequence in bat cells does not show any expression profile changes.

Show legend

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome128 143 129 136 160 845 161 204 144
Read_Max
batR. aegyptiacusTranscriptome 90 87 102 125 97 145 98 113 117
Read_Max
bat_genomeR. aegyptiacusGenome 145 130 92 99 85 79 83 172 123
DESeq
humanH. sapiensGenome 2633.36 2570.06 2471.15 2772.86 2537.41 13027.31 2966.83 2817.91 3170.62
DESeq
batR. aegyptiacusTranscriptome 583.22 605.52 718.04 652.04 662.43 699.05 633.96 557.04 542.44
DESeq
bat_genomeR. aegyptiacusGenome 1610.5 1703.98 1808.68 1702.42 1832.69 2082.13 1758.77 1636.64 1562.55

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 2633.36 2772.86 2966.83 0.07 0.17 0.1
7h 2570.06 2537.41 2817.91 -0.02 0.13 0.15
23h 2471.15 13027.31 3170.62 2.4 0.36 -2.04

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 2633.36 2570.06 2471.15 -0.04 -0.09 -0.06
Ebov 2772.86 2537.41 13027.31 -0.13 2.23 2.36
Marv 2966.83 2817.91 3170.62 -0.07 0.1 0.17

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 583.22 652.04 633.96 0.16 0.12 -0.04
7h 605.52 662.43 557.04 0.13 -0.12 -0.25
23h 718.04 699.05 542.44 -0.04 -0.4 -0.37

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 583.22 605.52 718.04 0.05 0.3 0.25
Ebov 652.04 662.43 699.05 0.02 0.1 0.08
Marv 633.96 557.04 542.44 -0.19 -0.22 -0.04