RAI1

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
RAI1 RAI1, SMCR, SMS,DKFZP434A139, KIAA1820, MGC12824 retinoic acid induced 1 NM_030665 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

This gene is located within the Smith-Magenis syndrome region on chromosome 17. It is highly similar to its mouse counterpart and is expressed at high levels mainly in neuronal tissues. The protein encoded by this gene includes a polymorphic polyglutamine tract in the N-terminal domain. We are a group of bioinformaticians trapped in a tower in eastern germany. Attracted by the call of fame and cheap beer we now realize there is no escape. 40 of us started out into unknown territory, however only six are left. We do not know how long we can last. If you find this message, please send help. Expression of the mouse counterpart in neurons is induced by retinoic acid. This gene is associated with both the severity of the phenotype and the response to medication in schizophrenic patients.

The human cells gene RAI1 and its bat cells homolog are upregulated in late Ebola virus infection.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome73 55 60 64 60 330 83 91 65
Read_Max
batR. aegyptiacusTranscriptome 58 53 47 49 51 98 48 69 63
Read_Max
bat_genomeR. aegyptiacusGenome 58 50 40 51 45 58 42 74 81
DESeq
humanH. sapiensGenome 2967.22 2290.61 2298.4 2590.35 2162.64 10258.61 2481.74 2480.59 2398.6
DESeq
batR. aegyptiacusTranscriptome 1337.66 1376.15 1358.13 1309.49 1424.62 1619.09 1034.43 1230.4 1271.08
DESeq
bat_genomeR. aegyptiacusGenome 2068.55 2022.51 2240.48 2077.67 2198.78 2257.05 1649.69 1721.49 2047.15

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 2967.22 2590.35 2481.74 -0.2 -0.26 -0.06
7h 2290.61 2162.64 2480.59 -0.08 0.11 0.2
23h 2298.4 10258.61 2398.6 2.16 0.06 -2.1

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 2967.22 2290.61 2298.4 -0.37 -0.37 0.0
Ebov 2590.35 2162.64 10258.61 -0.26 1.99 2.25
Marv 2481.74 2480.59 2398.6 -0.0 -0.05 -0.05

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 1337.66 1309.49 1034.43 -0.03 -0.37 -0.34
7h 1376.15 1424.62 1230.4 0.05 -0.16 -0.21
23h 1358.13 1619.09 1271.08 0.25 -0.1 -0.35

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 1337.66 1376.15 1358.13 0.04 0.02 -0.02
Ebov 1309.49 1424.62 1619.09 0.12 0.31 0.18
Marv 1034.43 1230.4 1271.08 0.25 0.3 0.05