CEP72

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
CEP72 KIAA1519, FLJ10565 centrosomal protein 72kDa NM_018140 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

The product of this gene is a member of the leucine-rich-repeat (LRR) superfamily of proteins. The protein is localized to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells.

The expression triples 23 h after Ebola infection in human cells, while it stays at a constant level in bat cells. An intron seems to be retained in all samples. An additional exon was found to be expressed after the last annotated exon reaching into the annotation of the downstream gene TPPP.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome24 35 25 25 33 115 33 52 19
Read_Max
batR. aegyptiacusTranscriptome 16 24 11 21 11 21 22 23 17
Read_Max
bat_genomeR. aegyptiacusGenome 78 90 41 68 64 36 43 110 60
DESeq
humanH. sapiensGenome 575.37 596.61 643.36 678.57 577.38 2222.28 570.31 618.1 475.08
DESeq
batR. aegyptiacusTranscriptome 118.62 106.29 90.17 120.04 94.08 80.56 121.14 143.11 100.72
DESeq
bat_genomeR. aegyptiacusGenome 1966.28 1778.82 1282.03 1754.76 1533.57 1116.13 1578.84 1922.1 1334.8

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 575.37 678.57 570.31 0.24 -0.01 -0.25
7h 596.61 577.38 618.1 -0.05 0.05 0.1
23h 643.36 2222.28 475.08 1.79 -0.44 -2.23

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 575.37 596.61 643.36 0.05 0.16 0.11
Ebov 678.57 577.38 2222.28 -0.23 1.71 1.94
Marv 570.31 618.1 475.08 0.12 -0.26 -0.38

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 118.62 120.04 121.14 0.02 0.03 0.01
7h 106.29 94.08 143.11 -0.18 0.43 0.61
23h 90.17 80.56 100.72 -0.16 0.16 0.32

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 118.62 106.29 90.17 -0.16 -0.4 -0.24
Ebov 120.04 94.08 80.56 -0.35 -0.58 -0.22
Marv 121.14 143.11 100.72 0.24 -0.27 -0.51