EPHA2
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| EPHA2 | ARCC2, CTPA, CTPP1, CTRCT6, ECK | EPH receptor A2 | NM_004431 |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
This gene belongs to the ephrin receptor subfamily of the protein-tyrosinekinase family. EPH and EPH-related receptors have been implicated inmediating developmental events, particularly in the nervous system.Receptors in the EPH subfamily typically have a single kinase domain and anextracellular region containing a Cys-rich domain and 2 fibronectin type IIIrepeats. The ephrin receptors are divided into 2 groups based on thesimilarity of their extracellular domain sequences and their affinities forbinding ephrin-A and ephrin-B ligands. This gene encodes a protein thatbinds ephrin-A ligands. Mutations in this gene are the cause of certaingenetically-related cataract disorders.
The gene is highly expressed in human cells and bat cells, and upregulated in earlyMarburg and late Ebola infection.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 263 | 294 | 208 | 227 | 254 | 972 | 341 | 445 | 280 |
Read_Max |  | R. aegyptiacus | Transcriptome | NA | NA | NA | NA | NA | NA | NA | NA | NA |
Read_Max |  | R. aegyptiacus | Genome | 122 | 141 | 161 | 116 | 110 | 151 | 84 | 236 | 293 |
DESeq | | H. sapiens | Genome | 6263.25 | 7030.98 | 4720.89 | 5868.67 | 4896.59 | 21284.73 | 6757.23 | 7892.19 | 6708.84 |
DESeq | | R. aegyptiacus | Transcriptome | NA | NA | NA | NA | NA | NA | NA | NA | NA |
DESeq | | R. aegyptiacus | Genome | 2107.22 | 2871.31 | 3865.05 | 2375.89 | 2958.87 | 4893.98 | 1904.96 | 2771.35 | 4092.6 |