MGEA5
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| MGEA5 | BC014201,MEA5, NCOAT, OGA | meningioma expressed antigen 5 (hyaluronidase) | NM_012215 |  |
 |
 |
 |
Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
The dynamic modification of cytoplasmic and nuclear proteins by O-linked N-acetylglucosamine (O-GlcNAc) addition and removal on serine and threonine residues is catalyzed by OGT (MIM 300255), which adds O-GlcNAc, and MGEA5, a glycosidase that removes O-GlcNAc modifications.
The gene is upregulated in Ebola infected human cells and bat cells cells.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 165 | 128 | 212 | 156 | 193 | 812 | 222 | 142 | 220 |
Read_Max |  | R. aegyptiacus | Transcriptome | 187 | 156 | 236 | 198 | 159 | 354 | 125 | 257 | 227 |
Read_Max |  | R. aegyptiacus | Genome | 339 | 309 | 293 | 234 | 208 | 305 | 158 | 473 | 368 |
DESeq | | H. sapiens | Genome | 3397.49 | 2446.66 | 5087.24 | 3474.38 | 3065.82 | 12561.48 | 3362.45 | 2242.38 | 5137.63 |
DESeq | | R. aegyptiacus | Transcriptome | 1772.86 | 1496.87 | 3129.36 | 2259.95 | 2247.03 | 3841.56 | 1560.59 | 2477.15 | 2276.12 |
DESeq | | R. aegyptiacus | Genome | 4872.74 | 5980.82 | 7327.31 | 4024.0 | 5730.23 | 9132.65 | 4228.24 | 6304.71 | 6150.88 |