HSPH1

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
HSPH1 HSPH1, HSP105, HSP105A, HSP105B, NY-CO-25,HSP105B, KIAA0201 heat shock 105kDa/110kDa protein 1 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

HSPH1 prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly.

The expression seems to be modulated in Ebola and Marburg infection of human cells and bat cells samples.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome608 1148 797 620 1464 2803 712 1570 655
Read_Max
batR. aegyptiacusTranscriptome 1300 1249 833 1476 1178 1294 766 1682 966
Read_Max
bat_genomeR. aegyptiacusGenome 1338 1490 646 1069 927 681 639 1866 971
DESeq
humanH. sapiensGenome 10537.53 17360.26 13575.89 9716.2 17442.86 39915.55 9476.57 17027.16 12813.21
DESeq
batR. aegyptiacusTranscriptome 14389.25 15016.0 12610.92 18990.13 18182.78 19486.11 13750.34 18794.76 12288.03
DESeq
bat_genomeR. aegyptiacusGenome 14081.97 17768.15 11020.54 15160.84 17185.11 18664.75 13518.0 16911.16 11223.82

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 10537.53 9716.2 9476.57 -0.12 -0.15 -0.04
7h 17360.26 17442.86 17027.16 0.01 -0.03 -0.03
23h 13575.89 39915.55 12813.21 1.56 -0.08 -1.64

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 10537.53 17360.26 13575.89 0.72 0.37 -0.35
Ebov 9716.2 17442.86 39915.55 0.84 2.04 1.19
Marv 9476.57 17027.16 12813.21 0.85 0.44 -0.41

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 14389.25 18990.13 13750.34 0.4 -0.07 -0.47
7h 15016.0 18182.78 18794.76 0.28 0.32 0.05
23h 12610.92 19486.11 12288.03 0.63 -0.04 -0.67

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 14389.25 15016.0 12610.92 0.06 -0.19 -0.25
Ebov 18990.13 18182.78 19486.11 -0.06 0.04 0.1
Marv 13750.34 18794.76 12288.03 0.45 -0.16 -0.61