HSPH1

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
HSPH1	HSPH1, HSP105, HSP105A, HSP105B, NY-CO-25,HSP105B, KIAA0201	heat shock 105kDa/110kDa protein 1		pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

HSPH1 prevents the aggregation of denatured proteins in cells under severe stress, on which the ATP levels decrease markedly.

The expression seems to be modulated in Ebola and Marburg infection of human cells and bat cells samples.

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source		Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max		H. sapiens	Genome	608	1148	797	620	1464	2803	712	1570	655
Read_Max		R. aegyptiacus	Transcriptome	1300	1249	833	1476	1178	1294	766	1682	966
Read_Max		R. aegyptiacus	Genome	1338	1490	646	1069	927	681	639	1866	971
DESeq		H. sapiens	Genome	10537.53	17360.26	13575.89	9716.2	17442.86	39915.55	9476.57	17027.16	12813.21
DESeq		R. aegyptiacus	Transcriptome	14389.25	15016.0	12610.92	18990.13	18182.78	19486.11	13750.34	18794.76	12288.03
DESeq		R. aegyptiacus	Genome	14081.97	17768.15	11020.54	15160.84	17185.11	18664.75	13518.0	16911.16	11223.82

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	10537.53	9716.2	9476.57	-0.12	-0.15	-0.04
7h	17360.26	17442.86	17027.16	0.01	-0.03	-0.03
23h	13575.89	39915.55	12813.21	1.56	-0.08	-1.64

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	10537.53	17360.26	13575.89	0.72	0.37	-0.35
Ebov	9716.2	17442.86	39915.55	0.84	2.04	1.19
Marv	9476.57	17027.16	12813.21	0.85	0.44	-0.41

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	14389.25	18990.13	13750.34	0.4	-0.07	-0.47
7h	15016.0	18182.78	18794.76	0.28	0.32	0.05
23h	12610.92	19486.11	12288.03	0.63	-0.04	-0.67

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	14389.25	15016.0	12610.92	0.06	-0.19	-0.25
Ebov	18990.13	18182.78	19486.11	-0.06	0.04	0.1
Marv	13750.34	18794.76	12288.03	0.45	-0.16	-0.61