SIK3

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
SIK3	QSK,FLJ12240, L19, KIAA0999, QSK	SIK family kinase 3	NM_025164	pdf		NONE

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

SIK3 (SIK family kinase 3) is a protein-coding gene. GO annotations related to this gene include protein serine/threonine kinase activity and magnesium ion binding. An important paralog of this gene is BRSK1.

The gene SIK3 is expressed throughout human cells and bat cells datasets without significant changes in expression rates.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source	Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max	H. sapiens	Genome	185	161	160	133	192	331	183	244	131
Read_Max	R. aegyptiacus	Transcriptome	193	191	105	151	155	346	136	165	238
Read_Max	R. aegyptiacus	Genome	202	158	89	170	124	197	109	195	248
DESeq	H. sapiens	Genome	3232.08	3111.61	2186.21	3578.18	2808.12	8841.37	3738.77	3222.38	2587.8
DESeq	R. aegyptiacus	Transcriptome	4010.99	3577.3	2672.5	2949.45	3063.97	6029.39	3212.52	2714.27	3247.92
DESeq	R. aegyptiacus	Genome	5493.22	3978.39	3962.13	4858.42	4255.82	8056.99	4529.62	3782.35	4516.41

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	3232.08	3578.18	3738.77	0.15	0.21	0.06
7h	3111.61	2808.12	3222.38	-0.15	0.05	0.2
23h	2186.21	8841.37	2587.8	2.02	0.24	-1.77

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	3232.08	3111.61	2186.21	-0.05	-0.56	-0.51
Ebov	3578.18	2808.12	8841.37	-0.35	1.31	1.65
Marv	3738.77	3222.38	2587.8	-0.21	-0.53	-0.32

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	4010.99	2949.45	3212.52	-0.44	-0.32	0.12
7h	3577.3	3063.97	2714.27	-0.22	-0.4	-0.17
23h	2672.5	6029.39	3247.92	1.17	0.28	-0.89

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	4010.99	3577.3	2672.5	-0.17	-0.59	-0.42
Ebov	2949.45	3063.97	6029.39	0.05	1.03	0.98
Marv	3212.52	2714.27	3247.92	-0.24	0.02	0.26

Differential transcriptional responses to Ebola and Marburg virus infection in cells from bats and humans

Supplemental Material