BAG3

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
BAG3 BCL2-associated athanogene 3 NM_004281 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

Inhibits the chaperone activity of HSP70/HSC70 by promoting substrate release. Has anti-apoptotic activity The profile changes on infected cells. A new annotation in bats is needed in order to compare the effect of profile change and viral response.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome109 112 91 89 137 409 96 187 95
Read_Max
batR. aegyptiacusTranscriptome 188 134 148 167 120 185 157 196 196
Read_Max
bat_genomeR. aegyptiacusGenome 206 171 128 129 114 115 141 250 201
DESeq
humanH. sapiensGenome 1085.81 1615.46 1011.7 1047.01 1248.07 4030.35 1152.77 1832.31 1118.79
DESeq
batR. aegyptiacusTranscriptome 1145.27 1184.63 1268.96 1138.26 1018.34 1308.56 1144.55 1094.9 963.18
DESeq
bat_genomeR. aegyptiacusGenome 1221.19 1243.08 1253.02 1284.72 1099.39 1498.61 1275.22 1210.83 961.5

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 1085.81 1047.01 1152.77 -0.05 0.09 0.14
7h 1615.46 1248.07 1832.31 -0.37 0.18 0.55
23h 1011.7 4030.35 1118.79 1.99 0.15 -1.85

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 1085.81 1615.46 1011.7 0.57 -0.1 -0.68
Ebov 1047.01 1248.07 4030.35 0.25 1.94 1.69
Marv 1152.77 1832.31 1118.79 0.67 -0.04 -0.71

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 1145.27 1138.26 1144.55 -0.01 -0.0 0.01
7h 1184.63 1018.34 1094.9 -0.22 -0.11 0.1
23h 1268.96 1308.56 963.18 0.04 -0.4 -0.44

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 1145.27 1184.63 1268.96 0.05 0.15 0.1
Ebov 1138.26 1018.34 1308.56 -0.16 0.2 0.36
Marv 1144.55 1094.9 963.18 -0.06 -0.25 -0.18