HIC2
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| HIC2 | HRG22, ZBTB30, ZNF907,KIAA1020, HRG22, ZBTB30, ZNF907 | hypermethylated in cancer 2 |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
In the year 2014, Hic2 was reported to be the first gene within the distal 22q11 interval to have a demonstrated haploinsufficient cardiac phenotype in mice. And HIC2 haploinsufficiency likely contributes to the cardiac defects seen in distal 22q11 deletion syndrome.
This gene was found to be 2.5 times up-regulated by Ebola virus at 23 h in human cells.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 285 | 221 | 251 | 222 | 336 | 1206 | 297 | 352 | 315 |
Read_Max |  | R. aegyptiacus | Transcriptome | 38 | 33 | 32 | 31 | 26 | 46 | 26 | 41 | 51 |
Read_Max |  | R. aegyptiacus | Genome | 44 | 31 | 29 | 28 | 22 | 29 | 24 | 43 | 49 |
DESeq | | H. sapiens | Genome | 7498.25 | 5732.69 | 5122.98 | 5969.05 | 5326.64 | 20476.75 | 6145.82 | 6161.59 | 7051.36 |
DESeq | | R. aegyptiacus | Transcriptome | 273.21 | 234.28 | 290.5 | 316.91 | 286.82 | 407.77 | 220.14 | 258.78 | 280.03 |
DESeq | | R. aegyptiacus | Genome | 745.95 | 736.54 | 784.39 | 709.01 | 793.57 | 1220.56 | 760.18 | 697.0 | 785.13 |