TMED7

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
TMED7 CGI-109, NM_181836, NP_861974, FLJ90481 transmembrane emp24 protein transport domain containing 7 NM_181836 pdf

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Description

Transmembrane emp24 protein transport domain containing 7 (TMED7) has a potential role in vesicular protein trafficking, mainly in the early secretory pathway. It appears to play a role in the biosynthesis of secreted cargo including processing and post-translational modifications.

This gene is significantly downregulated in the cells 23 h after Ebola infection in human cells. In bat cells, there seems to be no downregulation at this timepoint.

Show legend

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome724 559 673 502 779 197 678 626 580
Read_Max
batR. aegyptiacusTranscriptome NA NA NA NA NA NA NA NA NA
Read_Max
bat_genomeR. aegyptiacusGenome 1274 918 550 809 669 461 813 1348 983
DESeq
humanH. sapiensGenome 7808.77 5980.51 7486.9 5723.81 6851.74 1944.62 5658.97 5060.09 7214.46
DESeq
batR. aegyptiacusTranscriptome NA NA NA NA NA NA NA NA NA
DESeq
bat_genomeR. aegyptiacusGenome 10815.42 11229.68 7848.38 9995.31 11212.68 9404.17 13106.42 11407.32 8422.36

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 7808.77 5723.81 5658.97 -0.45 -0.46 -0.02
7h 5980.51 6851.74 5060.09 0.2 -0.24 -0.44
23h 7486.9 1944.62 7214.46 -1.94 -0.05 1.89

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 7808.77 5980.51 7486.9 -0.38 -0.06 0.32
Ebov 5723.81 6851.74 1944.62 0.26 -1.56 -1.82
Marv 5658.97 5060.09 7214.46 -0.16 0.35 0.51

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h NA NA NA NA NA NA
7h NA NA NA NA NA NA
23h NA NA NA NA NA NA

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock NA NA NA NA NA NA
Ebov NA NA NA NA NA NA
Marv NA NA NA NA NA NA